There have been case reports of neonatal sacrocoocygeal teratoma, metabolic acidosis, hypocalcemia, hypomagnesemia, renal tubular acidosis, and low birth weight following in utero exposure to acetazolamide. Drug interactions, dosing, and pregnancy and breastfeeding safety are provided. Its use in pregnant women has not been recommended because of reported teratogenic effects in rodents and rabbits. Background:Acetazolamide is the mainstay of medical therapy for idiopathic intracranial hypertension (IIH). Family & Pregnancy. Pregnancy category: C. Lactation: Enters breast milk; not recommended. It may be used long term for the treatment of open angle glaucoma and short term for acute angle closure glaucoma until surgery can be carried out. Its use in pregnant women has not been recommended because of reported teratogenic effects in rodents and rabbits. However, many physicians have reported the use of Diamox to treat IH symptoms after the first 20 weeks of pregnancy. Just diagnosed with PTC for first time, 21 weeks into pregnancy— likely caused by a heavy dosage of estrogen and progesterone in early pre- and pregnancy to support embryo implantation and funcion. A: Generally acceptable. One reported case of a teratoma in pregnancy associated with acetazolamide has limited its use particularly in the first trimester. You should not breast-feed while using this medicine. They conclude that while liberal use of acetazolamide should be avoided during pregnancy, the drug should remain a treatment option in pregnant women when clinically indicated. However, the safety of acetazolamide use during human pregnancy remains unclear. If the clinical situation warrants the use of acetazolamide in IIH, then the drug probably can be offered … Possible serious side effects include liver problems, seizures, and metabolic acidosis. Acetazolamide at high doses may produce birth defects in animals, but there is little clinical or experimental evidence to support any adverse effect of the drug on pregnancy outcomes in humans. Acetazolamide is the mainstay of medical therapy for idiopathic intracranial hypertension (IIH). Diamox (acetazolamide) is officially classified as a Class-C drug, which means its safety for use during pregnancy has not been established. However, the safety of acetazolamide use during human pregnancy remains unclear. All About Pregnancy. Am on a low dose of Diamox and will work up to 500 mg 2x daily. WebMD provides important information about Diamox Oral such as if you can you take Diamox Oral when you are pregnant or nursing or If Diamox Oral dangerous for children or adults over 60. Pregnancy Family & Pregnancy. Published data on the risk of acetazolamide therapy during pregnancy are unclear. Acetazolamide can pass into breast milk and may harm a nursing baby. However, recent large studies of pregnancy and acetazolamide have not found any association with teratoma [26,27]. Pregnancy Categories. Controlled studies in pregnant women show no evidence of fetal risk. Acetazolamide (Diamox, Diamox Sequels) used to remove excess fluid in the body in people with congestive heart failure; to treat seizures and glaucoma; and the prevention and treatment of altitude sickness. B: May be acceptable. View Abstract Journal of Neuro-Ophthalmology, March 2013 Getting Pregnant; First Trimester; ... Diamox Tablet Side Effects by Likelihood and Severity COMMON side effects. Tell your doctor if you are pregnant or plan to become pregnant. 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