Efficacy of blue light vs. red light in the treatment of psoriasis: A doubleblind, randomized comparative study. This should be the bare minimum requirement. Lasers in medical science,31(4), 789-809.
Journal of Cosmetic and Laser Therapy, 11(2), 125-128. If they only report the J/cm2 you can calculate the mW/cm2 using the recommended treatment time (in seconds). My top pick is the Omnilux Contour Mask (see below for more info). Stating at present, the published literature strongly suggests 830nm for all aspects of wound healing, pain, inti-inflammatory treatment and skin rejuvenation, with a combination of 415nm and 633nm for light-only treatment of active inflammatory acne vulgaris. Even within different studies on the same animal models, there can be contradictory findings. Photochemical & Photobiological Sciences,18(8), 1877-1909. But it doesnt make Light Salon any better than any of the other flexible masks that I cover in this post. The clinical and histological effect of homeuse, combination bluered LED phototherapy for mildtomoderate acne vulgaris in Korean patients: a doubleblind, randomized controlled trial. Karu and Kolyakov (2005) have pointed out that there are many pairs of wavelengths which actually inhibit cellular activity when used together, yet enhance activity when applied separately. The combo of 633nm red light and 415nm blue light is recommended because the red light also tackles inflammation and appears to improve the efficacy on noninflammatory lesions (Greaves et al 2015). Another major downside is that it doesnt include NIR. It looks like Shape A (which looks like Omnilux is available in the US and the other shape is sold in the UK). Im not sure whether the measurements include the bumps for the straps (the measurements for the Omnilux and other flex masks dont).
The term blue light can refer to a relatively wide range of wavelengths from violet (390425 nm), indigo (425450 nm), royal blue (450475 nm), blue green (475500 nm)and they have had very different results. Weinstabl, A., Hoff-Lesch, S., Merk, H. F., & Von Felbert, V. (2011). (, This is identical (not just in looks, in wavelength, irradiance) to Light Salon. Mainly the price and the 1 year warranty are some downsides. Springer, Cham. But onebigdownside of this mask is that it doesnt have NIR. This ones parameters are pretty good (this is the mask that FaceLITE used as the predicate device in their 510(k) submission.) In a meta-analysis of of low-power lasers in tissue repair and pain control (Enwemeka et al., 2004), 633nm had the largest effect size and 780 had the smallest. If the cell is damaged or compromised, it will repair itself, or be repaired. Karu, T. I., & Kolyakov, S. F. (2005). If you are excited about the blue light for infrequent breakouts you may want to consider getting a, 1 year warranty (kind of shocking given the price that it doesnt have a 2 year warranty IMHO), Here are the specific irradiance for each wavelength (as provided by the company), There are some things that I dont love about this masks parameters. Note: You dont want to know the joule (J), you want to know the J/cm2. Another downside is that you get 4 uses before needing to charge it again (that is really low and would be annoying in my opinion). Ideally, you would want to see 633nm), the blue wavelength is better (405nm to 420nm wavelength, 415nm is the ideal), but blue light comes with downsides to consider and eye protection is necessary which this doesnt provide.
If the cell has a function, e.g., collagen and elastin synthesis by fibroblasts, it will perform that function more efficiently. Posts like this take me a ton of time, so I appreciate your support if you do choose to shop through my links. At higher doses (e.g., 50 J/cm2 ) and after 24- hour exposure, it was shown that cellular viability was significantly reduced to 74%, leading to a significant increase of cellular injury to 365% of the control.. Kwon, H. H., Lee, J. Best results are not seen immediately post treatment, but later on at 4, 8 and 12 weeks or more. The results Ive seen from using LED mask for a year, Key Parameters (what you really want to look for when assessing masks), How does Low Level Light Therapy Work? A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings. Kleinpenning, M. M., Otero, M. E., van Erp, P. E. J., Gerritsen, M. J. P., & van de Kerkhof, P. C. M. (2012). But you could lay it on your chest, for example, and press and hold it down. Laser-Tissue Interactions. This matters because research has found that wavelengths between 700-770 have been reported to not have any significant activity (Gupta et al., 2014; Karu, 2010; Wu et al 2012). Journal of Photochemistry and Photobiology B: Biology, 155, 78-85. If you are using blue light to treat acne, it may be best to use a handheld device to just target spots as there is some evidence that it could increase hyperpigmentation. enhancing cellular mitochondrial function and ATP production through interacting with a photoreceptor called cytochrome c oxidase. Orbit,28(4), 214-218. So it could make it easier to find a good deal (or at least see which store has the best Rakuten cash back). I would personally skip the blue setting entirely and just use the red setting. LLLT has been also effectively used in wound healing applications following surgical aesthetic and resurfacing procedures, post-procedural erythema, and in conjunction with photodynamic therapy (Ablon, 2018). Keep to well-proven wavelengths, applied singly unless they are the well-tested combinations. Lima, A. M. C. T., da Silva Sergio, L. P., & da Fonseca, A. D. S. (2020). Therefore, it offers very little to dermal renewal and repair. Because these products only work if you use them). Whilst the perceivable dangers of LLLT are mainly related to retinal damage (both clinician and patient) and skin burn (mainly related to shorter UV wavelengths), the safety of LLLT is well documented in a number of standards such as US Code of Federal Regulations, American National Standards Institute and the International Standards Manual, and other laser safety books and review articles [21, 22]. Res. Aim to purchase products that use evidence-based wavelengths and that report all key parameters. Russell, B. Journal of Cosmetic and Laser Therapy,7(3-4), 196-200. A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emitting diode light on facial rejuvenation. This comes with a little neck (NOT chest, just neck) attachment, which is a nice perk. Trelles, M. A., Allones, I., & Mayo, E. (2006). If the medicine is incorrect, i.e., an irradiance which is too low (resulting in no effect) or too high (resulting in photothermal damage), no amount of playing around with the dose will achieve the optimum result. Journal of Investigative Dermatology, 129(12), 2751-2759. A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase. But the same research that applies to face masks applies to those devices, so you are able to assess their potential efficacy using the parameters above. I was happy to see this had a good irradiance and used Red and NIR in the right wavelengths (and that the company disclosed it but that was, 2 year warranty (BUTbe sure to register your device within ONE MONTH of buying it or the warranty is void. (2006). So while it doesnt have my ideal wavelengths, using the mask consistently is what is most important. Not saying I recommend this mask, but if you do check it out, you can save 25% at. Three wavelengths of light that have demonstrated several therapeutic applications are. In an animal study, Blue light (430510nm) delayed the barrier recovery, whereas red light (550670nm) accelerated it. (2007b). Wu et al (2012) used a 730-nm laser on TBI in mice and found it to be ineffective while 660 and 810 nm lasers were effective. Medical Laser Application, 21(3), 165-175. How can you avoid wasting your money? Greaves, A. J. This one is available LOTS of places. Fournier N, Fritz K,Mordon S. Use of nonthermal blue (405-to 420-nm) and near-infrared light (850- to 900-nm) dualwavelength system in combination with glycolic acid peels and topical vitamin C for skin photorejuvenation. Photomedicine: Advances in Clinical Practice. If the device has an imprecise wavelength, then that means you arent getting as pure or high quality a light. Despite the low irradiance, a recent study by Kim et al 2020 found some positive outcomes. Very expensive mask and the company is very guarded about the wavelengths and power. That is because the same dose (fluence) can be associated with different results based on the irradiance and treatment time (Almeida-Lopes et a., 2001; Barolet et al., 2016). But since it does include blue wavelengths I was happy to see that it comes with protective goggles (blue wavelengths require eye protection whereas red does not). This mask is similar to the flexible shape of the Omnilux. This one has a lot of unnecessary wavelengths (personally, I would Just use the 630nm setting on this) and it has some wavelengths (439, 450-460nm) I would actively avoid using. Photobiomodulation stimulates fibroblast proliferation, collagen synthesis, growth factors, and extracellular matrix production by activating cellular mitochondrial respiratory pathways (Ablon, 2018). The main benefits seen in clinical trials of LLLT for skin rejuvenation (in other words, excluding research focused specifically on inflammation) are: Biopsies have shown increased collagen and elastin production that would account for many of these benefits. The use of wavelengths in LLLT at 400nm or lower should be utilized in practice with extreme caution. (Serrage et al., 2020). Light-emitting diode 585 nm photomodulation inhibiting melanin synthesis and inducing autophagy in human melanocytes. Proposed mechanisms of photobiomodulation or low-level light therapy. Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris. Among clinical studies focused on skin rejuvenation, irradiance values ranges from 6 mW/cm2 to 150 mW/cm2, with the median being 55 mW/cm2. beam area (cm2) at the tissue surface (not the size of the aperture).
2006;32(9):11406. They like that on the charger it counted down the minutes that remain. ~590 nm (yellow): it has effect only in the epidermis with poor penetration into the dermis. (2007a). Lasers in Medical Science, 33(7), 1431-1439. If the irradiance is too high, the photon energy will be transformed to excessive heat in the target tissue; the mask may get hot and can inhibit the treatment or even create undesired outcomes. Alternatively, using too low of an irradiance and the photons absorption will be insufficient to achieve the goal. Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update. ~530 nm (green): it might have some benefit for pigmented epidermal conditions and superficial skin conditions like stretch marks but its use for these conditions has not been proven yet (De Cordova, 2021). Journal of Photochemistry and Photobiology B: Biology,88(1), 51-67. One thing to keep in mind is that the irradiance and fluence used in vitro studies are often different from those used in clinical studies. Zheng C., Rajabi-Estarabadi A., Hirsch M.M., Nouri K. (2020) Light Emitting Diodes and Low Level Laser Light Therapy. Consulting Room 2020;3(03):1315. Calderhead RG. Dermatology, 223(3), 251-259. Some companies like to highlight the number of wavelengths used, but often those additional wavelengths have very little or no published work to back up the claims of the manufacturer (and they seem more like a marketing gimmick than anything), and a careful consideration of the wavelength/penetration ratio will rule out many of the shorter visible light wavelengths (Calderhead, 2018). Journal of Cosmetic and Laser Therapy, 8(2), 71-75. The internal temperature may be the same, but the skin of the turkey will be charred in the 800 degree oven). I love knowing that they have really incredible customer service!). Journal of biophotonics,9(11-12), 1122. And you can do a single color at a timeso I would stick to red or an occasional blue treatment if you have a breakout all over your face (but really, you could just spot treat a pimple with a handheld device that combines 415nm and 630nm which is more effective than 415nm alone). Visible radiation affects epidermal permeability barrier recovery: selective effects of red and blue light. Light emitting diodes technology-based photobiomodulation therapy (PBMT) for dermatology and aesthetics: Recent applications, challenges, and perspectives. But I want to note that I appreciate how helpful and transparent the contact at Dermashine was nonetheless, I was shocked at how low the irradiance it (I actually thought it was a typo so I confirmed it was 0.5mw/cm2). Typically, there are no safety concerns for LEDs unless they are blue or if the device uses a very strong power (>100 mW/cm2). The only difference is it is missing the strap for the top of the head and it is, Then for other territories, pricing varies a bit depending on where you are so Current Body gave me a code to just give people. Woodruff, L. D., Bounkeo, J. M., Brannon, W. M., Dawes, K. S., Barham, C. D., Waddell, D. L., & Enwemeka, C. S. (2004). Trelles and Allones (2006) found applying red light (633nm; 80mw/cm2; 96j/cm2) after laser resurfacing cut healing time in half. The effects of narrowbands of visible light upon some skin disorders: a review. Low-Level Laser (Light) Therapy for Cosmetics and Dermatology. It has been shown many times that there is a dose-rate effect and if the dose is delivered too quickly the beneficial effects are diminished. Then you take 18/600 = 0.03 W/cm2 and multiply that times 1000 to get 30 mW/cm2. But a higher irradiance isnt always better. Chen, L., Xu, Z., Jiang, M., Zhang, C., Wang, X., & Xiang, L. (2018). Irradiation with a wavelength of 415nm can destroy the P.acnes but it doesnt address the associated inflammatory problem. I also only focused on face masks, versus hand held devices or panels because I had to narrow it down somehow and since I enjoy using the mask bc of its convenience that is what I focused on. This has good wavelengths and irradiance, but it is super expensive. Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures. (Also, this isnt mentioned below but take into consideration convenience. Some studies of using a wavelength of 420-443nm found that unintentional, It is usually used with red and/or NIR as otherwise it can cause skin darkening (Calderhead, 2020), The use of blue light in particular (400500 nm) is additionally surrounded by significant controversy relating to the premise that the margin between safe blue light and potentially damaging ultraviolet (UV) light is not well defined. (Serrage et al., 2020). I found out about this one from @ms_hannah_e on IG and it has great specs! And its cheaper. Light stimulus will be insufficient to trigger a cellular function if it is delivered below the recommended dose and will inhibit activation of these responses if a dose higher than indicated is delivered. Journal of the European Academy of Dermatology and Venereology, 25(1), 49-58. Light irradiation with low power density has been reported as a noninvasive, non-carcinogenic, atraumatic, with no known side effect therapy to many diseases and undesired conditions. Does the mask manufacturer provide the specific wavelengths? I was sad to find out they wont reveal their irradiance. Green and yellow light have very poor penetration into living tissue and have rarely been studied. Nam, C. H., Park, B. C., Kim, M. H., Choi, E. H., & Hong, S. P. (2017). AlmeidaLopes, L., Rigau, J., Amaro Zngaro, R., GuidugliNeto, J., & Marques Jaeger, M. M. (2001). New addition to list as of 6/11/2021. For example, to repair damage from UV rays, your skin needs to be able to repair cellular and DNA damage (which is similar to what it does during wound healing). Lasers in medical science,29(1), 257-265. Current Status of Light-Emitting Diode Phototherapy in Dermatological Practice.
(2016). Laser therapy,24(4), 277-289. Barolet, D., Christiaens, F., & Hamblin, M. R. (2016). First, while it does have, If you are ok with uncertainty and not knowing the irradiance and having to use it for 20 min instead of 10, this isnt a bad option because at least it uses good wavelengths. T. Nakanishi-Ueda, H.J. I have written to the company to ask if they will report the irradiance. (Oh and the shape is sillywouldnt you want full coverage on your forehead rather than having a heart shape?). So take claims about the benefits of green, orange and yellow light with a grain of salt. Combined visible light and infrared light-emitting diode (LED) therapy enhances wound healing after laser ablative resurfacing of photodamaged facial skin. A. It uses evidence based wavelengths for red and NIR and has a great irradiance. You can email companies and ask them to tell you the irradiance (or power density) reported in mW/cm2. Medical Research Archives, 6(1). Also, you wont know what you are working with and you may be wasting your time and money using the device. There is no fixed value of fluence that always produces a positive LLLT effect. Phototherapy with light emitting diodes: treating a broad range of medical and aesthetic conditions in dermatology. They didnt provide the irradiance but they provided the fluence, and using that to calculate the irradiance gave a shockingly low number (1.5 mW/cm2). Where did you see that it was 880nm? Major downside right off the bat is that it uses a blue wavelength that isnt the one that has been found to help with acne (415nm) but has been found to induce hyperpigmentation. A difference of even 5nm from the peak can in some cases dramatically lower the action potential (Calderhead, 2018). Hope this was helpful! A higher irradiance often means a shorter treatment time. Springer, Cham. If you come across a mask that you are curious about, I recommend identifying the wavelengths used, the irradiance and the treatment time. Keep in mind that lower irradiance (<50mW/cm2) is less likely to induce skin hyperthermia (heat) leading to potential deleterious effects (Barolet et al 2016). Also, one nice thing about the Qure is that it has an app where you can just use the blue+red light on one portion of your face. It is the power density of a beam that will determine more than anything else (apart from wavelength) the magnitude of the bioeffect in the target tissue (Calderhead, 2018). Exact action spectra for cellular responses relevant to phototherapy. Therefore, LED light therapy aids skin rejuvenation through increasing collagen production and decreasing collagen degradation (which can be seen with the tightening of lax skin and the reduction of wrinkles). It has been reported for a continuous wave system that shorter irradiation times with a higher intensity (irradiance) got significantly better results in first passage human gingival fibroblast proliferation. Caution must be emphasized especially for epileptic and photophobic patients especially if LEDs are pulsed. (Barolet, 2008). The efficacy of laser therapy in wound repair: a meta-analysis of the literature. Serrage, H., Heiskanen, V., Palin, W. M., Cooper, P. R., Milward, M. R., Hadis, M., & Hamblin, M. R. (2019). If you are using a blue light, it is advised that you use eye protection. This is the mask that I used from Nov. 2019-Dec. 2020. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. (Mechanism of Action), Things to keep in mind (including notes about blue wavelengths), Some IG posts Ive done on the LED use, results Ive seen, and. Photobiomodulation, photomedicine, and laser surgery, 37(1), 4-16. Ask what the nominal wavelength of the system is, and what is the deviation either side. Denda, M., & Fuziwara, S. (2008). If LED therapy is administered several times prior to a UV insult, a mechanical trauma such as a CO2 laser treatment or a surgery, one may prevent undesirable consequences such as sunburn, postinflammatory hyperpigmentation (PIH), or hypertrophic scarring, respectively. Barolet goes on to talk about those applications, ocular symptoms (typically with blue light), discontinue sessions if any side effects occur, Many companies cite evidence from in vitro or animal studies. The Journal of clinical and aesthetic dermatology, 11(2), 21. De Cordova, J. Sanclemente, G., Medina, L., Villa, J. F., Barrera, L. M., & Garcia, H. I. Here is an updated cheat sheet with discount codes for the masks I recommend: The goal is to avoid a mask that fails to deliver the power, penetration, and clinical benefits claimed by the manufacturers. Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IRA radiation. a 4 month update can be found in my Omnilux Story highlights! This is the most gimmicky LED maskapparently this one also has rose quartz crystals. Although a more recent in vitro study by Chen at el (2018) offers very preliminary evidence that LLLT with yellow light at 585nm can help reduce pigmentation. Barolet, D. (2018). Does the mask use wavelengths with published scientific evidence showing its effectiveness? If it uses Blue light, the best choice is 415nm. In: Madan V. (eds) Practical Introduction to Laser Dermatology. Handbook of Lasers in Dermatology, 307327. (2010). Lasers in surgery and medicine,44(3), 218-226. Calderhead, R. G., & Omi, T. (2014). Red light can help this process because it stimulates collagen synthesis and fibroblast formation, anti-inflammatory action, energy production in mitochondria, and DNA repair (Barolet, 2018; de Freitas & Hamblin, 2016; Hamblin, 2016).
Journal of Cosmetic and Laser Therapy, 11(2), 125-128. If they only report the J/cm2 you can calculate the mW/cm2 using the recommended treatment time (in seconds). My top pick is the Omnilux Contour Mask (see below for more info). Stating at present, the published literature strongly suggests 830nm for all aspects of wound healing, pain, inti-inflammatory treatment and skin rejuvenation, with a combination of 415nm and 633nm for light-only treatment of active inflammatory acne vulgaris. Even within different studies on the same animal models, there can be contradictory findings. Photochemical & Photobiological Sciences,18(8), 1877-1909. But it doesnt make Light Salon any better than any of the other flexible masks that I cover in this post. The clinical and histological effect of homeuse, combination bluered LED phototherapy for mildtomoderate acne vulgaris in Korean patients: a doubleblind, randomized controlled trial. Karu and Kolyakov (2005) have pointed out that there are many pairs of wavelengths which actually inhibit cellular activity when used together, yet enhance activity when applied separately. The combo of 633nm red light and 415nm blue light is recommended because the red light also tackles inflammation and appears to improve the efficacy on noninflammatory lesions (Greaves et al 2015). Another major downside is that it doesnt include NIR. It looks like Shape A (which looks like Omnilux is available in the US and the other shape is sold in the UK). Im not sure whether the measurements include the bumps for the straps (the measurements for the Omnilux and other flex masks dont).
The term blue light can refer to a relatively wide range of wavelengths from violet (390425 nm), indigo (425450 nm), royal blue (450475 nm), blue green (475500 nm)and they have had very different results. Weinstabl, A., Hoff-Lesch, S., Merk, H. F., & Von Felbert, V. (2011). (, This is identical (not just in looks, in wavelength, irradiance) to Light Salon. Mainly the price and the 1 year warranty are some downsides. Springer, Cham. But onebigdownside of this mask is that it doesnt have NIR. This ones parameters are pretty good (this is the mask that FaceLITE used as the predicate device in their 510(k) submission.) In a meta-analysis of of low-power lasers in tissue repair and pain control (Enwemeka et al., 2004), 633nm had the largest effect size and 780 had the smallest. If the cell is damaged or compromised, it will repair itself, or be repaired. Karu, T. I., & Kolyakov, S. F. (2005). If you are excited about the blue light for infrequent breakouts you may want to consider getting a, 1 year warranty (kind of shocking given the price that it doesnt have a 2 year warranty IMHO), Here are the specific irradiance for each wavelength (as provided by the company), There are some things that I dont love about this masks parameters. Note: You dont want to know the joule (J), you want to know the J/cm2. Another downside is that you get 4 uses before needing to charge it again (that is really low and would be annoying in my opinion). Ideally, you would want to see 633nm), the blue wavelength is better (405nm to 420nm wavelength, 415nm is the ideal), but blue light comes with downsides to consider and eye protection is necessary which this doesnt provide.
If the cell has a function, e.g., collagen and elastin synthesis by fibroblasts, it will perform that function more efficiently. Posts like this take me a ton of time, so I appreciate your support if you do choose to shop through my links. At higher doses (e.g., 50 J/cm2 ) and after 24- hour exposure, it was shown that cellular viability was significantly reduced to 74%, leading to a significant increase of cellular injury to 365% of the control.. Kwon, H. H., Lee, J. Best results are not seen immediately post treatment, but later on at 4, 8 and 12 weeks or more. The results Ive seen from using LED mask for a year, Key Parameters (what you really want to look for when assessing masks), How does Low Level Light Therapy Work? A prospective, randomized, placebo-controlled, double-blinded, and split-face clinical study on LED phototherapy for skin rejuvenation: clinical, profilometric, histologic, ultrastructural, and biochemical evaluations and comparison of three different treatment settings. Kleinpenning, M. M., Otero, M. E., van Erp, P. E. J., Gerritsen, M. J. P., & van de Kerkhof, P. C. M. (2012). But you could lay it on your chest, for example, and press and hold it down. Laser-Tissue Interactions. This matters because research has found that wavelengths between 700-770 have been reported to not have any significant activity (Gupta et al., 2014; Karu, 2010; Wu et al 2012). Journal of Photochemistry and Photobiology B: Biology, 155, 78-85. If you are using blue light to treat acne, it may be best to use a handheld device to just target spots as there is some evidence that it could increase hyperpigmentation. enhancing cellular mitochondrial function and ATP production through interacting with a photoreceptor called cytochrome c oxidase. Orbit,28(4), 214-218. So it could make it easier to find a good deal (or at least see which store has the best Rakuten cash back). I would personally skip the blue setting entirely and just use the red setting. LLLT has been also effectively used in wound healing applications following surgical aesthetic and resurfacing procedures, post-procedural erythema, and in conjunction with photodynamic therapy (Ablon, 2018). Keep to well-proven wavelengths, applied singly unless they are the well-tested combinations. Lima, A. M. C. T., da Silva Sergio, L. P., & da Fonseca, A. D. S. (2020). Therefore, it offers very little to dermal renewal and repair. Because these products only work if you use them). Whilst the perceivable dangers of LLLT are mainly related to retinal damage (both clinician and patient) and skin burn (mainly related to shorter UV wavelengths), the safety of LLLT is well documented in a number of standards such as US Code of Federal Regulations, American National Standards Institute and the International Standards Manual, and other laser safety books and review articles [21, 22]. Res. Aim to purchase products that use evidence-based wavelengths and that report all key parameters. Russell, B. Journal of Cosmetic and Laser Therapy,7(3-4), 196-200. A randomized, placebo-controlled, single-blinded, split-faced clinical trial evaluating the efficacy and safety of KLOX-001 gel formulation with KLOX light-emitting diode light on facial rejuvenation. This comes with a little neck (NOT chest, just neck) attachment, which is a nice perk. Trelles, M. A., Allones, I., & Mayo, E. (2006). If the medicine is incorrect, i.e., an irradiance which is too low (resulting in no effect) or too high (resulting in photothermal damage), no amount of playing around with the dose will achieve the optimum result. Journal of Investigative Dermatology, 129(12), 2751-2759. A controlled trial to determine the efficacy of red and near-infrared light treatment in patient satisfaction, reduction of fine lines, wrinkles, skin roughness, and intradermal collagen density increase. But the same research that applies to face masks applies to those devices, so you are able to assess their potential efficacy using the parameters above. I was happy to see this had a good irradiance and used Red and NIR in the right wavelengths (and that the company disclosed it but that was, 2 year warranty (BUTbe sure to register your device within ONE MONTH of buying it or the warranty is void. (2006). So while it doesnt have my ideal wavelengths, using the mask consistently is what is most important. Not saying I recommend this mask, but if you do check it out, you can save 25% at. Three wavelengths of light that have demonstrated several therapeutic applications are. In an animal study, Blue light (430510nm) delayed the barrier recovery, whereas red light (550670nm) accelerated it. (2007b). Wu et al (2012) used a 730-nm laser on TBI in mice and found it to be ineffective while 660 and 810 nm lasers were effective. Medical Laser Application, 21(3), 165-175. How can you avoid wasting your money? Greaves, A. J. This one is available LOTS of places. Fournier N, Fritz K,Mordon S. Use of nonthermal blue (405-to 420-nm) and near-infrared light (850- to 900-nm) dualwavelength system in combination with glycolic acid peels and topical vitamin C for skin photorejuvenation. Photomedicine: Advances in Clinical Practice. If the device has an imprecise wavelength, then that means you arent getting as pure or high quality a light. Despite the low irradiance, a recent study by Kim et al 2020 found some positive outcomes. Very expensive mask and the company is very guarded about the wavelengths and power. That is because the same dose (fluence) can be associated with different results based on the irradiance and treatment time (Almeida-Lopes et a., 2001; Barolet et al., 2016). But since it does include blue wavelengths I was happy to see that it comes with protective goggles (blue wavelengths require eye protection whereas red does not). This mask is similar to the flexible shape of the Omnilux. This one has a lot of unnecessary wavelengths (personally, I would Just use the 630nm setting on this) and it has some wavelengths (439, 450-460nm) I would actively avoid using. Photobiomodulation stimulates fibroblast proliferation, collagen synthesis, growth factors, and extracellular matrix production by activating cellular mitochondrial respiratory pathways (Ablon, 2018). The main benefits seen in clinical trials of LLLT for skin rejuvenation (in other words, excluding research focused specifically on inflammation) are: Biopsies have shown increased collagen and elastin production that would account for many of these benefits. The use of wavelengths in LLLT at 400nm or lower should be utilized in practice with extreme caution. (Serrage et al., 2020). Light-emitting diode 585 nm photomodulation inhibiting melanin synthesis and inducing autophagy in human melanocytes. Proposed mechanisms of photobiomodulation or low-level light therapy. Combination blue (415 nm) and red (633 nm) LED phototherapy in the treatment of mild to severe acne vulgaris. Among clinical studies focused on skin rejuvenation, irradiance values ranges from 6 mW/cm2 to 150 mW/cm2, with the median being 55 mW/cm2. beam area (cm2) at the tissue surface (not the size of the aperture).
2006;32(9):11406. They like that on the charger it counted down the minutes that remain. ~590 nm (yellow): it has effect only in the epidermis with poor penetration into the dermis. (2007a). Lasers in Medical Science, 33(7), 1431-1439. If the irradiance is too high, the photon energy will be transformed to excessive heat in the target tissue; the mask may get hot and can inhibit the treatment or even create undesired outcomes. Alternatively, using too low of an irradiance and the photons absorption will be insufficient to achieve the goal. Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update. ~530 nm (green): it might have some benefit for pigmented epidermal conditions and superficial skin conditions like stretch marks but its use for these conditions has not been proven yet (De Cordova, 2021). Journal of Photochemistry and Photobiology B: Biology,88(1), 51-67. One thing to keep in mind is that the irradiance and fluence used in vitro studies are often different from those used in clinical studies. Zheng C., Rajabi-Estarabadi A., Hirsch M.M., Nouri K. (2020) Light Emitting Diodes and Low Level Laser Light Therapy. Consulting Room 2020;3(03):1315. Calderhead RG. Dermatology, 223(3), 251-259. Some companies like to highlight the number of wavelengths used, but often those additional wavelengths have very little or no published work to back up the claims of the manufacturer (and they seem more like a marketing gimmick than anything), and a careful consideration of the wavelength/penetration ratio will rule out many of the shorter visible light wavelengths (Calderhead, 2018). Journal of Cosmetic and Laser Therapy, 8(2), 71-75. The internal temperature may be the same, but the skin of the turkey will be charred in the 800 degree oven). I love knowing that they have really incredible customer service!). Journal of biophotonics,9(11-12), 1122. And you can do a single color at a timeso I would stick to red or an occasional blue treatment if you have a breakout all over your face (but really, you could just spot treat a pimple with a handheld device that combines 415nm and 630nm which is more effective than 415nm alone). Visible radiation affects epidermal permeability barrier recovery: selective effects of red and blue light. Light emitting diodes technology-based photobiomodulation therapy (PBMT) for dermatology and aesthetics: Recent applications, challenges, and perspectives. But I want to note that I appreciate how helpful and transparent the contact at Dermashine was nonetheless, I was shocked at how low the irradiance it (I actually thought it was a typo so I confirmed it was 0.5mw/cm2). Typically, there are no safety concerns for LEDs unless they are blue or if the device uses a very strong power (>100 mW/cm2). The only difference is it is missing the strap for the top of the head and it is, Then for other territories, pricing varies a bit depending on where you are so Current Body gave me a code to just give people. Woodruff, L. D., Bounkeo, J. M., Brannon, W. M., Dawes, K. S., Barham, C. D., Waddell, D. L., & Enwemeka, C. S. (2004). Trelles and Allones (2006) found applying red light (633nm; 80mw/cm2; 96j/cm2) after laser resurfacing cut healing time in half. The effects of narrowbands of visible light upon some skin disorders: a review. Low-Level Laser (Light) Therapy for Cosmetics and Dermatology. It has been shown many times that there is a dose-rate effect and if the dose is delivered too quickly the beneficial effects are diminished. Then you take 18/600 = 0.03 W/cm2 and multiply that times 1000 to get 30 mW/cm2. But a higher irradiance isnt always better. Chen, L., Xu, Z., Jiang, M., Zhang, C., Wang, X., & Xiang, L. (2018). Irradiation with a wavelength of 415nm can destroy the P.acnes but it doesnt address the associated inflammatory problem. I also only focused on face masks, versus hand held devices or panels because I had to narrow it down somehow and since I enjoy using the mask bc of its convenience that is what I focused on. This has good wavelengths and irradiance, but it is super expensive. Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures. (Also, this isnt mentioned below but take into consideration convenience. Some studies of using a wavelength of 420-443nm found that unintentional, It is usually used with red and/or NIR as otherwise it can cause skin darkening (Calderhead, 2020), The use of blue light in particular (400500 nm) is additionally surrounded by significant controversy relating to the premise that the margin between safe blue light and potentially damaging ultraviolet (UV) light is not well defined. (Serrage et al., 2020). I found out about this one from @ms_hannah_e on IG and it has great specs! And its cheaper. Light stimulus will be insufficient to trigger a cellular function if it is delivered below the recommended dose and will inhibit activation of these responses if a dose higher than indicated is delivered. Journal of the European Academy of Dermatology and Venereology, 25(1), 49-58. Light irradiation with low power density has been reported as a noninvasive, non-carcinogenic, atraumatic, with no known side effect therapy to many diseases and undesired conditions. Does the mask manufacturer provide the specific wavelengths? I was sad to find out they wont reveal their irradiance. Green and yellow light have very poor penetration into living tissue and have rarely been studied. Nam, C. H., Park, B. C., Kim, M. H., Choi, E. H., & Hong, S. P. (2017). AlmeidaLopes, L., Rigau, J., Amaro Zngaro, R., GuidugliNeto, J., & Marques Jaeger, M. M. (2001). New addition to list as of 6/11/2021. For example, to repair damage from UV rays, your skin needs to be able to repair cellular and DNA damage (which is similar to what it does during wound healing). Lasers in medical science,29(1), 257-265. Current Status of Light-Emitting Diode Phototherapy in Dermatological Practice.
(2016). Laser therapy,24(4), 277-289. Barolet, D., Christiaens, F., & Hamblin, M. R. (2016). First, while it does have, If you are ok with uncertainty and not knowing the irradiance and having to use it for 20 min instead of 10, this isnt a bad option because at least it uses good wavelengths. T. Nakanishi-Ueda, H.J. I have written to the company to ask if they will report the irradiance. (Oh and the shape is sillywouldnt you want full coverage on your forehead rather than having a heart shape?). So take claims about the benefits of green, orange and yellow light with a grain of salt. Combined visible light and infrared light-emitting diode (LED) therapy enhances wound healing after laser ablative resurfacing of photodamaged facial skin. A. It uses evidence based wavelengths for red and NIR and has a great irradiance. You can email companies and ask them to tell you the irradiance (or power density) reported in mW/cm2. Medical Research Archives, 6(1). Also, you wont know what you are working with and you may be wasting your time and money using the device. There is no fixed value of fluence that always produces a positive LLLT effect. Phototherapy with light emitting diodes: treating a broad range of medical and aesthetic conditions in dermatology. They didnt provide the irradiance but they provided the fluence, and using that to calculate the irradiance gave a shockingly low number (1.5 mW/cm2). Where did you see that it was 880nm? Major downside right off the bat is that it uses a blue wavelength that isnt the one that has been found to help with acne (415nm) but has been found to induce hyperpigmentation. A difference of even 5nm from the peak can in some cases dramatically lower the action potential (Calderhead, 2018). Hope this was helpful! A higher irradiance often means a shorter treatment time. Springer, Cham. If you come across a mask that you are curious about, I recommend identifying the wavelengths used, the irradiance and the treatment time. Keep in mind that lower irradiance (<50mW/cm2) is less likely to induce skin hyperthermia (heat) leading to potential deleterious effects (Barolet et al 2016). Also, one nice thing about the Qure is that it has an app where you can just use the blue+red light on one portion of your face. It is the power density of a beam that will determine more than anything else (apart from wavelength) the magnitude of the bioeffect in the target tissue (Calderhead, 2018). Exact action spectra for cellular responses relevant to phototherapy. Therefore, LED light therapy aids skin rejuvenation through increasing collagen production and decreasing collagen degradation (which can be seen with the tightening of lax skin and the reduction of wrinkles). It has been reported for a continuous wave system that shorter irradiation times with a higher intensity (irradiance) got significantly better results in first passage human gingival fibroblast proliferation. Caution must be emphasized especially for epileptic and photophobic patients especially if LEDs are pulsed. (Barolet, 2008). The efficacy of laser therapy in wound repair: a meta-analysis of the literature. Serrage, H., Heiskanen, V., Palin, W. M., Cooper, P. R., Milward, M. R., Hadis, M., & Hamblin, M. R. (2019). If you are using a blue light, it is advised that you use eye protection. This is the mask that I used from Nov. 2019-Dec. 2020. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. (Mechanism of Action), Things to keep in mind (including notes about blue wavelengths), Some IG posts Ive done on the LED use, results Ive seen, and. Photobiomodulation, photomedicine, and laser surgery, 37(1), 4-16. Ask what the nominal wavelength of the system is, and what is the deviation either side. Denda, M., & Fuziwara, S. (2008). If LED therapy is administered several times prior to a UV insult, a mechanical trauma such as a CO2 laser treatment or a surgery, one may prevent undesirable consequences such as sunburn, postinflammatory hyperpigmentation (PIH), or hypertrophic scarring, respectively. Barolet goes on to talk about those applications, ocular symptoms (typically with blue light), discontinue sessions if any side effects occur, Many companies cite evidence from in vitro or animal studies. The Journal of clinical and aesthetic dermatology, 11(2), 21. De Cordova, J. Sanclemente, G., Medina, L., Villa, J. F., Barrera, L. M., & Garcia, H. I. Here is an updated cheat sheet with discount codes for the masks I recommend: The goal is to avoid a mask that fails to deliver the power, penetration, and clinical benefits claimed by the manufacturers. Multiple roles of cytochrome c oxidase in mammalian cells under action of red and IRA radiation. a 4 month update can be found in my Omnilux Story highlights! This is the most gimmicky LED maskapparently this one also has rose quartz crystals. Although a more recent in vitro study by Chen at el (2018) offers very preliminary evidence that LLLT with yellow light at 585nm can help reduce pigmentation. Barolet, D. (2018). Does the mask use wavelengths with published scientific evidence showing its effectiveness? If it uses Blue light, the best choice is 415nm. In: Madan V. (eds) Practical Introduction to Laser Dermatology. Handbook of Lasers in Dermatology, 307327. (2010). Lasers in surgery and medicine,44(3), 218-226. Calderhead, R. G., & Omi, T. (2014). Red light can help this process because it stimulates collagen synthesis and fibroblast formation, anti-inflammatory action, energy production in mitochondria, and DNA repair (Barolet, 2018; de Freitas & Hamblin, 2016; Hamblin, 2016).